An androgen-independent mechanism underlying the androgenic effects of 3-methylcholanthrene, a potent aryl hydrocarbon receptor agonist.
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DOI: 10.1093/toxres/tfaa027
Abstract: Aryl hydrocarbon receptor (AhR) and androgen receptor (AR) are ligand-activated transcription factors with profound cross-talk between their signal transduction pathways. Previous studies have shown that AhR agonists activate the transcription of AR-regulated genes in an… read more here.
Keywords: mechanism; androgen independent; hydrocarbon receptor; aryl hydrocarbon ... See more keywords