Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.135994
Abstract: Current available antidepressants have various adverse reactions and slow pharmacodynamics, so it is necessary to find novel antidepressants for effective treatment. Xanthoceraside (XAN), a novel triterpenoid saponin extracted from the fruit husks of Xanthoceras sorbifolium… read more here.
Keywords: effects mice; xan; signaling pathway; bdnf signaling ... See more keywords
5-O-methylcneorumchromone K Exerts Antinociceptive Effects in Mice via Interaction with GABAA Receptors
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22073413
Abstract: The proper pharmacological control of pain is a continuous challenge for patients and health care providers. Even the most widely used medications for pain treatment are still ineffective or unsafe for some patients, especially for… read more here.
Keywords: effects mice; antinociceptive effects; methylcneorumchromone exerts; exerts antinociceptive ... See more keywords