Protective effects of morphine in a rat model of post-traumatic stress disorder: Role of hypothalamic-pituitary-adrenal axis and beta- adrenergic system
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112867
Abstract: Post-traumatic stress disorder (PTSD) arises after tremendous traumatic experiences. Recently, we have reported that morphine has time-dependent protective effects against behavioral and morphological deficits in the single prolonged stress (SPS) as an experimental model of… read more here.
Keywords: beta adrenergic; stress; effects morphine; protective effects ... See more keywords
Effect of three doses of nalbuphine on reversal of sedation and cardiopulmonary effects of morphine-acepromazine in healthy dogs.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary anaesthesia and analgesia"
DOI: 10.1016/j.vaa.2019.03.001
Abstract: OBJECTIVE To evaluate the efficacy of three doses of nalbuphine in reversing sedative and cardiopulmonary effects of morphine-acepromazine in dogs. STUDY DESIGN Prospective, randomized experimental trial. ANIMALS A group of eight healthy Beagle dogs, aged… read more here.
Keywords: effects morphine; three doses; doses nalbuphine; sedation ... See more keywords
Stimulatory and inhibitory effects of morphine on pentylenetetrazol-induced epileptic activity in rat
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2020.1759591
Abstract: Abstract Aims The present study attempts to evaluate the effects of different doses of morphine on experimental epileptiform activity caused by pentylenetetrazol (PTZ) in rats. Methods Thirty adult male rats were assigned to saline (n = 5),… read more here.
Keywords: spike count; inhibitory effects; effects morphine; stimulatory inhibitory ... See more keywords
Effects of morphine/CP55940 mixtures on an impulsive choice task in rhesus monkeys
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000339
Abstract: µ-Opioid receptor agonists are commonly used to treat pain despite their adverse effects. In preclinical studies, cannabinoid receptor agonists increase the potency of opioids for producing antinociceptive but not reinforcing effects. It is unknown whether… read more here.
Keywords: cp55940 mixtures; cp55940; morphine cp55940; effects morphine ... See more keywords
D-Cysteine Ethyl Ester Reverses the Deleterious Effects of Morphine on Breathing and Arterial Blood–Gas Chemistry in Freely-Moving Rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.883329
Abstract: Cell-penetrant thiol esters including the disulfides, D-cystine diethyl ester and D-cystine dimethyl ester, and the monosulfide, L-glutathione ethyl ester, prevent and/or reverse the deleterious effects of opioids, such as morphine and fentanyl, on breathing and… read more here.
Keywords: deleterious effects; gas; ester; chemistry ... See more keywords