Psychotropic Effects of a New Pyrazolo[C]Pyridine Derivate GIZh-72 are Related to Functional Activity of Atp-Sensitive Potassium Channels
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-020-04729-5
Abstract: We studied the influence of intraperitoneal injection of ATP-sensitive potassium channels inhibitor glibenclamide in doses of 0.01, 0.1, 1, and 10 mg/kg on the effects of a new pyrazolo[C]pyridine derivative GIZh-72 (4,6-dimethyl-2-(4-chlorphenyl)-2,3-dihydro-1Hpyrazolo[ 4,3-C]pyridine-3-on, chloral hydrate;… read more here.
Keywords: potassium channels; sensitive potassium; effects new; atp sensitive ... See more keywords
Probing the effects of some new physics models in B→ Dsτν¯ decay
Sign Up to like & getrecommendations! Published in 2020 at "Nuclear Physics B"
DOI: 10.1016/j.nuclphysb.2020.114997
Abstract: Abstract Recent measurements on the semi-leptonic b → c l ν ¯ l and b → s l + l − decays imply possible hints of Lepton Flavor Universality (LFU) violation and therefore have attracted… read more here.
Keywords: probing effects; effects new; physics; model ... See more keywords
Antitumor effects of new glycoconjugated PtII agents dual-targeting GLUT1 and Pgp proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt02455a
Abstract: A novel and highly efficient dual-targeting PtII system was designed to improve the drug delivery capacity and selectivity in cancer treatment. The dual-targeting monofunctional PtII complexes (1-8) having glycosylated pendants as tridentated ligand were achieved… read more here.
Keywords: dual targeting; glut1 pgp; effects new; antitumor effects ... See more keywords
Investigation on effects of new physics in transitions
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DOI: 10.1088/1674-1137/abf489
Abstract: Anomalies in decays induced by ( ) transitions may imply lepton flavor universality violations, which raises questions on such phenomena in the D decays induced by transitions. Current measurements of the pure leptonic and semi-leptonic… read more here.
Keywords: scalar operators; physics; effects new; new physics ... See more keywords
PD26-05 EFFECTS OF A NEW ORAL TESTOSTERONE UNDECANOATE (TLANDO) THERAPY ON LIVER
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000883.05
Abstract: INTRODUCTION AND OBJECTIVE:Oral methyltestosterone (MT) was approved for a testosterone replacement therapy (TRT) in males with a deficiency of endogenous testosterone. Due to its liver toxicity, t... read more here.
Keywords: oral testosterone; effects new; testosterone; pd26 effects ... See more keywords
Antidepressant-like effects of a new dihydro isoquinoline and its chemical precursors in mice: involvement of serotonin and dopaminergic systems
Sign Up to like & getrecommendations! Published in 2020 at "Canadian Journal of Chemistry"
DOI: 10.1139/cjc-2020-0291
Abstract: Abstract This study was aimed to synthesize novel 2-(2-bromophenyl)-N-phenethylacetamides and benzylisoquinoline (BIQ) derivatives to be evaluated as antidepressant-like agents in mice. The N-phene... read more here.
Keywords: effects new; like effects; isoquinoline chemical; new dihydro ... See more keywords
Cytotoxic effects of new-generation bulk-fill composites on human dental pulp stem cells.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2018.64.3.11
Abstract: This study was performed to evaluate possible DNA damage in cells of human origin exposed to dental composites in vitro using a cytotoxic assay. Five bulk-fill composites were filled in molds and irradiated for 20… read more here.
Keywords: fill composites; bulk fill; cytotoxic effects; effects new ... See more keywords
The Effects of the New Therapeutic Treatments for Diabetes Mellitus on the Male Reproductive Axis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.821113
Abstract: One of the complications of chronic hyperglycemia and insulin resistance due to type 2 diabetes mellitus (T2DM) on the hypothalamic-pituitary-gonadal axis in men, is the high prevalence of hypogonadotropic hypogonadism, which has been recently defined… read more here.
Keywords: new therapeutic; treatments diabetes; effects new; axis ... See more keywords
Antitumor Effects of a New Retinoate of the Fungal Cytotoxin Illudin M in Brain Tumor Models
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DOI: 10.3390/ijms23169056
Abstract: While the fungal metabolite illudin M (1) is indiscriminately cytotoxic in cancer and non-malignant cells, its retinoate 2 showed a greater selectivity for the former, especially in a cerebral context. Illudin M killed malignant glioma… read more here.
Keywords: fungal cytotoxin; illudin; effects new; retinoate fungal ... See more keywords