THU0347 TESTING THE IN VITRO EFFECTS OF NINTEDANIB ON CIRCULATING FIBROCYTES AND RESIDENT SKIN FIBROBLASTS FROM THE SAME SYSTEMIC SCLEROSIS PATIENTS: PRELIMINARY RESULTS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6909
Abstract: Background: The fibrosis in systemic sclerosis (SSc) progresses from microvascular alterations, immune system activation, and increased extracellular matrix protein synthesis into the skin and internal organs, primarily mediated by myofibroblasts.1 Myofibroblasts are characterized by a… read more here.
Keywords: col1; effects nintedanib; circulating fibrocytes; treatment ... See more keywords
Effects of nintedanib on markers of epithelial damage in subjects with IPF: data from the INMARK trial
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DOI: 10.1183/13993003.congress-2020.5187
Abstract: Introduction: The INMARK trial investigated effects of nintedanib on blood biomarkers in subjects with IPF. Aim: To investigate the effect of nintedanib on markers of epithelial damage. Methods: Subjects (n=346) with IPF and FVC ≥80%… read more here.
Keywords: markers epithelial; effects nintedanib; subjects ipf; epithelial damage ... See more keywords