Mechanisms and effects of NLRP3 in digestive cancers
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-023-01783-6
Abstract: Inflammasomes are thought to be important mediators of host defense against microbial pathogens and maintenance of gastrointestinal tract homeostasis. They can modulate caspase-1 to promote IL-18 and IL-1β secretion and promote phagocytosis induced by bacterial… read more here.
Keywords: system; role; mechanisms effects; effects nlrp3 ... See more keywords
Neuroimmune modulatory effects of the NLRP3 inflammasome: the role of sex and living environment in brain affecting conditions
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1711656
Abstract: The NLRP3 inflammasome is a master regulator of neuroinflammation, linking systemic perturbations to brain dysfunction and thereby influencing overall brain health. Its sensitivity to biological sex and environmental factors suggests that NLRP3 may act both… read more here.
Keywords: neuroimmune modulatory; brain; effects nlrp3; nlrp3 inflammasome ... See more keywords