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1
Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.814241
Abstract: Opioids are the most widely used analgesics and therefore have often been the focus of pharmacological research. Macrophages are the most plastic cells in the hematopoietic system. They show great functional diversity in various organism…
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Keywords:
system;
regulate immune;
opioids regulate;
system focusing ... See more keywords
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2
Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19042387
Abstract: Humans have used opioids to suppress moderate to severe pain for thousands of years. However, the long-term use of opioids has several adverse effects, such as opioid tolerance, opioid-induced hyperalgesia, and addiction. In addition, the…
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Keywords:
side effects;
opioid induced;
trpv1 receptors;
effects opioids ... See more keywords