Abstract 565: Effects of PCSK9 Inhibition on Plasma PCSK9 Concentration and Hepatic PCSK9 Expression
Sign Up to like & getrecommendations! Published in 2018 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvb.38.suppl_1.565
Abstract: Background: We previously reported a marked (~7-fold) increase in plasma PCSK9 concentrations in patients treated with monoclonal antibodies blocking PCSK9 action. It is unclear whether this pronou... read more here.
Keywords: plasma pcsk9; 565 effects; pcsk9; abstract 565 ... See more keywords
Pleiotropic Effects of PCSK9: Focus on Thrombosis and Haemostasis
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DOI: 10.3390/metabo12030226
Abstract: The proprotein convertase subtilisin/keying 9 (PCSK9) is a serine protease that has gained importance in recent years as a drug target, mainly due to its effect on cholesterol metabolism in promoting the degradation of the… read more here.
Keywords: thrombosis haemostasis; effects pcsk9; focus thrombosis; pleiotropic effects ... See more keywords