Prediction of ligand effects in platinum-amyloid-β coordination.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2017.05.003
Abstract: Ligand field molecular mechanics (LFMM) and semi-empirical Parametric Model 7 (PM7) methods are applied to a series of six PtII-Ligand systems binding to the N-terminal domain of the amyloid-β (Aβ) peptide. Molecular dynamics using a… read more here.
Keywords: coordination; peptide; effects platinum; prediction ligand ... See more keywords
The side effects of platinum-based chemotherapy drugs: a review for chemists.
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt00838h
Abstract: The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse… read more here.
Keywords: effects platinum; platinum based; based chemotherapy; side ... See more keywords