GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109501
Abstract: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid metabolism. Here, we examine whether PPARβ/δ activation effects depend on growth differentiation factor 15 (GDF15), a… read more here.
Keywords: effects ppar; gdf15; ampk; activation ... See more keywords
Effects Of PPARγ2 Pro12Ala Variant On Adipocyte Phenotype Dependent Of DHA
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s214526
Abstract: Background Peroxisome proliferator-activated receptor γ2 (PPARγ2) plays a critical role in the regulation of adipocyte differentiation and adipocytokine production. The Pro12Ala variant is the most common mutation in the PPARγ2 gene. Its effect appears to… read more here.
Keywords: dha; pro12ala variant; ppar pro12ala; effects ppar ... See more keywords