Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function
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DOI: 10.1007/s00213-018-5006-5
Abstract: RationaleGrowing evidence supports a role for the microbiota in regulating gut-brain interactions and, thus, psychiatric disorders. Despite substantial scientific efforts to delineate the mechanism of action of psychotropic medications at a central nervous system (CNS)… read more here.
Keywords: drugs microbiome; gut; differential effects; effects psychotropic ... See more keywords
Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice
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DOI: 10.3390/biom12101535
Abstract: Polypharmacy is commonly used to treat psychiatric disorders. These combinations often include drugs with sterol biosynthesis inhibiting side effects, including the antipsychotic aripiprazole (ARI), and antidepressant trazodone (TRZ). As the effects of psychotropic medications are… read more here.
Keywords: effects psychotropic; ari trz; biosynthesis; sterol biosynthesis ... See more keywords
Effects of Psychotropic Drugs on Ribosomal Genes and Protein Synthesis
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DOI: 10.3390/ijms23137180
Abstract: Altered protein synthesis has been implicated in the pathophysiology of several neuropsychiatric disorders, particularly schizophrenia. Ribosomes are the machinery responsible for protein synthesis. However, there remains little information on whether current psychotropic drugs affect ribosomes… read more here.
Keywords: effects psychotropic; synthesis; ribosomal genes; psychotropic drugs ... See more keywords
Effects of Psychotropic Drugs on Seizure Threshold during Electroconvulsive Therapy
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DOI: 10.4306/pi.2017.14.5.647
Abstract: Objective To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. Methods We examined clinical data from 43 patients. ST was titrated at each treatment session. We examined associations… read more here.
Keywords: seizure threshold; threshold electroconvulsive; drugs seizure; effects psychotropic ... See more keywords