Short- and long-term effects of rapamycin on ischemic damage and apoptotic changes in torsion of rat testes
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01965-4
Abstract: Rapamycin has antioxidant defense mechanisms and immune suppressive effects. To detect the short- and long-term effects of rapamycin on ischemic damage and apoptotic changes in torsion of rat testes, mature male albino Wistar rats (… read more here.
Keywords: term; long term; effects rapamycin; short long ... See more keywords
Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions
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DOI: 10.1111/epi.16975
Abstract: Infantile spasms may evolve into persistent epilepsies including Lennox‐Gastaut syndrome. We compared adult epilepsy outcomes in models of infantile spasms due to structural etiology (multiple‐hit model) or focal cortical inflammation and determined the anti‐epileptogenic effects… read more here.
Keywords: infantile spasms; effects rapamycin; antiepileptogenic effects; due structural ... See more keywords
The Effects of Rapamycin on the Intestinal Graft in a Rat Model of Cold Ischemia Perfusion and Preservation
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DOI: 10.3390/metabo12090794
Abstract: Attenuating the rheological and structural consequences of intestinal ischemia-reperfusion-injury (IRI) is important in transplant proceedings. Preconditioning is an often-proposed remedy. This technique uses physical or pharmacological methods to manipulate key ischemia pathways, such as oxidation,… read more here.
Keywords: ischemia; cold ischemia; perfusion; effects rapamycin ... See more keywords