Synergistic antitumor effects of rhein and doxorubicin in hepatocellular carcinoma cells.
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DOI: 10.1002/jcb.27514
Abstract: The aim of this study was to investigate the synergistic antitumor activity of rhein and doxorubicin (DOX) and to elucidate the underlying mechanisms in hepatocellular SMMC-7721 and HepG2 cells. Cell growth curves, caspase-3 activity, and… read more here.
Keywords: hepatocellular carcinoma; synergistic antitumor; rhein doxorubicin; antitumor effects ... See more keywords
The anti-obesity effects of rhein on improving insulin resistance (IR) and blood lipid levels are involved in endoplasmic reticulum stress (ERs), inflammation, and oxidative stress in vivo and vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1969196
Abstract: Rhein extensive biological effects including anti-inflammatory, antioxidant stress, and improving glucose and lipid metabolism. In the present study, the effects of rhein were examined on endoplasmic reticulum stress (ERs) and inflammation in obesity-induced rats. SD… read more here.
Keywords: stress; blood; obesity; ers inflammation ... See more keywords
Research Progress on the Positive and Negative Regulatory Effects of Rhein on the Kidney: A Review of Its Molecular Targets
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DOI: 10.3390/molecules27196572
Abstract: Currently, both acute kidney injury (AKI) and chronic kidney disease (CKD) are considered to be the leading public health problems with gradually increasing incidence rates around the world. Rhein is a monomeric component of anthraquinone… read more here.
Keywords: effects rhein; review; kidney; positive negative ... See more keywords