Effects of rigidity on the selectivity of protein kinase inhibitors.
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DOI: 10.1016/j.ejmech.2018.01.053
Abstract: Established strategies for discovering selective kinase inhibitors are target-centric as they often target certain structural or reactive features in the target kinase. In the absence of such prominent features, there is a lack of general… read more here.
Keywords: kinase inhibitors; rigidity selectivity; kinase; effects rigidity ... See more keywords