Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000640
Abstract: Inhibition of phosphodiesterase 4 (PDE4) is a promising pharmacological strategy for the treatment of cerebral ischemic conditions. To increase the relevance and increase the translational value of preclinical studies, it is important to conduct experiments… read more here.
Keywords: roflumilast; mice; effects roflumilast; cerebral ischemia ... See more keywords
Effects of Roflumilast on subclinical atherosclerosis in COPD - a randomized controlled trial
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DOI: 10.1183/1393003.congress-2017.pa693
Abstract: Background: COPD is associated with an excess atherosclerotic risk. Both, COPD and atherosclerosis are mediated by systemic inflammation. Roflumilast, as an anti-inflammatory drug, revealed potential atheroprotective effects in patients with COPD. Aims: To investigate the… read more here.
Keywords: systemic inflammation; copd; effects roflumilast; roflumilast ... See more keywords