Effects of strong and moderate CYP3A4 inducers on the pharmacokinetics of fedratinib in healthy adult participants
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-021-04292-4
Abstract: Fedratinib is an oral and selective Janus kinase 2 inhibitor that is indicated for treatment of adults with intermediate-2 or high-risk primary or secondary myelofibrosis. Fedratinib is metabolized by cytochrome P450s (CYPs), primarily CYP3A4. The… read more here.
Keywords: moderate cyp3a4; healthy adult; strong moderate; rifampin ... See more keywords
Quantum and quasi-classical effects in the strong field ionization and subsequent excitation of nitrogen molecules.
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DOI: 10.1364/oe.469492
Abstract: The processes leading to the N2 + lasing are rather complex and even the population distribution after the pump laser excitation is unknown. In this paper, we study the population distribution at electronic and vibrational… read more here.
Keywords: ionization; effects strong; excitation; quantum quasi ... See more keywords