Effects of strong and moderate CYP3A4 inducers on the pharmacokinetics of fedratinib in healthy adult participants
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-021-04292-4
Abstract: Fedratinib is an oral and selective Janus kinase 2 inhibitor that is indicated for treatment of adults with intermediate-2 or high-risk primary or secondary myelofibrosis. Fedratinib is metabolized by cytochrome P450s (CYPs), primarily CYP3A4. The… read more here.
Keywords: moderate cyp3a4; healthy adult; strong moderate; rifampin ... See more keywords
Synergistic activating effects of a strong Lewis acid (metal ion) and a strong BrØnsted acid enable KMnO4 to oxidize CH4 at room temperature
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/d5qi01117e
Abstract: The search for reagents that can oxidize methane (CH4) under mild conditions has long been a challenge for chemists. In this work, we report the synergistic effects of a strong... read more here.
Keywords: synergistic activating; ch4; strong lewis; activating effects ... See more keywords
Effects of strong capacitive coupling between meta-atoms in rf SQUID metamaterials
Sign Up to like & getrecommendations! Published in 2024 at "Superconductor Science and Technology"
DOI: 10.1088/1361-6668/ad54f8
Abstract: We consider, for the first time, the effects of strong capacitive and inductive coupling between radio frequency superconducting quantum interference devices (rf SQUIDs) in an overlapping metamaterial geometry when driven by rf flux at and… read more here.
Keywords: capacitive coupling; coupling meta; strong capacitive; squid metamaterials ... See more keywords
Effects of Strong Turbulence for Water Waves
Sign Up to like & getrecommendations! Published in 2025 at "JETP Letters"
DOI: 10.1134/s0021364025607973
Abstract: The results of direct numerical simulation of plane-symmetric turbulence of water waves for potential flows within the framework of conformal variables taking into account low-frequency pumping and high-frequency viscous dissipation are presented. In this model,… read more here.
Keywords: turbulence water; strong turbulence; turbulence; effects strong ... See more keywords
Quantum and quasi-classical effects in the strong field ionization and subsequent excitation of nitrogen molecules.
Sign Up to like & getrecommendations! Published in 2022 at "Optics express"
DOI: 10.1364/oe.469492
Abstract: The processes leading to the N2 + lasing are rather complex and even the population distribution after the pump laser excitation is unknown. In this paper, we study the population distribution at electronic and vibrational… read more here.
Keywords: ionization; effects strong; excitation; quantum quasi ... See more keywords