Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2019.1581174
Abstract: Abstract The aim of this study was to investigate the effects of sulforaphane (SFN) on lipopolysaccharide (LPS)-induced liver failure, and to elucidate underlying mechanisms. SFN, a natural isothiocyanate present in cruciferous vegetables such as broccoli… read more here.
Keywords: modulation inflammatory; sulforaphane modulation; effects sulforaphane; inflammatory pathways ... See more keywords
Protective effects of sulforaphane on STZ‐induced diabetic retinopathy via activation of Nrf2/HO‐1 antioxidant pathway and inhibition of NADPH oxidase
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/j.1755-3768.2017.01557
Abstract: Purpose To investigate the protective effects of sulforaphane, an Nrf2 activator, on streptozotocin (STZ)-induced diabetic retinopathy. Methods 8 wk male C57BL/6 mice were intraperitoneally injected with streptozotocin (STZ, 45 mg/kg) for 5 consective days. Animals with fasting… read more here.
Keywords: stz induced; stz; induced diabetic; effects sulforaphane ... See more keywords
Comparative Effects of Sulforaphane and Allyl Isothiocyanate on 3T3-L1 Adipogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nutrition and Metabolism"
DOI: 10.1155/2022/8705163
Abstract: Sulforaphane and allyl isothiocyanate, naturally occurring isothiocyanates, have been reported to inhibit adipocyte differentiation, but little is known about how they compare in terms of their potency and mechanism of action. In the present study,… read more here.
Keywords: differentiation; effects sulforaphane; sulforaphane allyl; comparative effects ... See more keywords
Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105397
Abstract: Nuclear factor erythroid 2-related factor 2 (NRF2) is a key transcription factor involved in protection against initiation of carcinogenesis in normal cells. Notably, recent studies have demonstrated that aberrant activation of NRF2 accelerates the proliferation… read more here.
Keywords: promoting effects; tumor promoting; treated mice; hepatocarcinogenesis ... See more keywords
Effects of Sulforaphane-Induced Cell Death upon Repeated Passage of Either P-Glycoprotein-Negative or P-Glycoprotein-Positive L1210 Cell Variants
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DOI: 10.3390/ijms231810818
Abstract: The expression of the membrane ABCB1 transporter in neoplastic cells is one of the most common causes of reduced sensitivity to chemotherapy. In our previous study, we investigated the effect of a single culture of… read more here.
Keywords: cell death; cell; sulforaphane induced; induced cell ... See more keywords
Examination of Novel Immunomodulatory Effects of L-Sulforaphane
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DOI: 10.3390/nu13020602
Abstract: The dietary isothiocyanate L-sulforaphane (LSF), derived from cruciferous vegetables, is reported to have several beneficial biological properties, including anti-inflammatory and immunomodulatory effects. However, there is limited data on how LSF modulates these effects in human… read more here.
Keywords: lsf; examination novel; effects sulforaphane; immunomodulatory effects ... See more keywords