Effects of the 5'‐Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase. Implications for Repurposing Antiviral Agents Against SARS‐CoV‐2
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DOI: 10.1002/cmdc.202200399
Abstract: Repurposing of antiviral drugs affords a rapid and effective strategy to develop therapies to counter pandemics such as COVID‐19. SARS‐CoV‐2 replication is closely linked to the metabolism of cytosine‐containing nucleotides, especially cytidine‐5′‐triphosphate (CTP), such that… read more here.
Keywords: ctp; effects triphosphate; repurposing antiviral; ctp synthase ... See more keywords