In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2019.172840
Abstract: In the present study, we examined whether LDK1258, which produces strong CB1 receptor allosteric effects in in vitro assays, would elicit in vivo effects consistent with allosteric activity. In initial studies, LDK1258 reduced food consumption… read more here.
Keywords: cb1 receptor; receptor allosteric; effects vivo; receptor ... See more keywords
The effects of ex vivo ozone treatment on human erythrocyte carbonic anhydrase enzyme
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DOI: 10.1080/13813455.2017.1371194
Abstract: Abstract Ozone autohemotherapy is used in the treatment of some diseases. Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes and play a role in homeostatic mechanisms. The aim of this study was to investigate the effects… read more here.
Keywords: treatment; enzyme; vivo ozone; effects vivo ... See more keywords
Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets
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DOI: 10.1111/jth.15694
Abstract: Ex vivo assays of platelet function critically inform mechanistic and clinical hematology studies, where effects of divergent blood processing methods on platelet composition are apparent, but unspecified. read more here.
Keywords: processing; effects vivo; vivo blood; preanalytical processing ... See more keywords
Toward a Holistic Understanding and Models of Nonphotochemical Quenching Effects on In Vivo Fluorometry of Chlorophyll a in Coastal Waters
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DOI: 10.1111/php.13693
Abstract: Nonphotochemical quenching (NPQ) is known to depress in vivo fluorescence (IVF) of chlorophyll a (Chla) in aquatic environments, which makes it difficult to interpret the hour‐to‐hour variations in Chla measured by in situ fluorometers. We… read more here.
Keywords: chlorophyll; ivf; effects vivo; nonphotochemical quenching ... See more keywords
Effects of in- vivo Application of Cold Atmospheric Plasma on the Leukocyte of Balb/c Mice
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DOI: 10.17582/journal.aavs/2019/7.4.250.255
Abstract: | The current study included the direct effect of CAP on a number of leukocytes in the laboratory mouse by exposing the skin to CAP using the floating electrode dielectric barrier discharge (FE-DBD).The study was… read more here.
Keywords: vivo application; application cold; group; exposure ... See more keywords