Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats
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DOI: 10.1007/s00213-017-4641-6
Abstract: Rationale and objectivesDesensitization of neuronal nicotinic acetylcholine receptors holds promise as an effective treatment of tobacco addiction. Previously, we found that sazetidine-A (Saz-A), which selectively desensitizes α4β2 nicotinic receptors, significantly decreased intravenous (IV) nicotine self-administration… read more here.
Keywords: self administration; administration; desensitizing agents; efficacies nicotinic ... See more keywords