Abstract A070: Optimal efficacious dose prediction of a novel protein degrader ASP3082 selectively targeting KRAS G12D using quantitative systems pharmacology
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DOI: 10.1158/1535-7163.targ-25-a070
Abstract: KRAS is a membrane-bound protein and a member of the RAS family of GTPases. It acts as a molecular switch to turn on or off receptor tyrosine kinase signal transduction by binding to GTP or… read more here.
Keywords: cancer; pharmacology; model; efficacious dose ... See more keywords