Translatability of in vitro potency to clinical efficacious exposure: A retrospective analysis of FDA-approved targeted small molecule oncology drugs.
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DOI: 10.1111/cts.13532
Abstract: In vitro potency is one of the important parameters representing efficacy potential of drugs and commonly used as benchmark of efficacious exposure at early clinical development. There are limited numbers of studies which systematically investigate… read more here.
Keywords: oncology; efficacious exposure; vitro potency; small molecule ... See more keywords