Bringing the HEET: The Argument for High-Efficacy Early Treatment for Pediatric-Onset Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Neurotherapeutics"
DOI: 10.1007/s13311-017-0568-1
Abstract: Pediatric-onset multiple sclerosis (POMS) is rarer than adult-onset disease, and represents a different diagnostic and treatment challenge to clinicians. We review POMS clinical and radiographic presentations, and explore important differences between POMS and adult-onset MS… read more here.
Keywords: high efficacy; treatment; early treatment; efficacy early ... See more keywords
Efficacy of early treatment in patients with cobalamin C disease identified by newborn screening: a 16-year experience
Sign Up to like & getrecommendations! Published in 2017 at "Genetics in Medicine"
DOI: 10.1038/gim.2016.214
Abstract: Purpose:Despite implementation of newborn screening (NBS), outcomes in cobalamin C disease (cblC) remain poor. Therapy with hydroxycobalamin and betaine is widely used, but dietary recommendations vary among metabolic centers. We present a longitudinal analysis of… read more here.
Keywords: metabolic control; efficacy early; newborn screening; cobalamin disease ... See more keywords
Do early interventions prevent PTSD? A systematic review and meta-analysis of the safety and efficacy of early interventions after sexual assault
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Psychotraumatology"
DOI: 10.1080/20008198.2019.1682932
Abstract: ABSTRACT Objective: To review the safety and efficacy of early interventions after sexual assault in reducing or preventing posttraumatic stress disorder (PTSD). Method: Systematic searches were performed on studies (1980–2018) that examined the efficacy of… read more here.
Keywords: sexual assault; interventions sexual; safety efficacy; safety ... See more keywords
Hypothesis: Efficacy of early treatments with some NSAIDs in COVID‐19: Might it also depend on their direct and/or indirect zinc chelating ability?
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15989
Abstract: The present work argues for the involvement of the zinc chelating ability of some non‐steroidal anti‐inflammatory drugs as an additive mechanism able to increase their efficacy against COVID‐19. read more here.
Keywords: efficacy early; hypothesis efficacy; chelating ability; zinc chelating ... See more keywords
The efficacy of early immunosuppression in a morphea patient complicated with pulmonary interstitial fibrosis
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DOI: 10.1111/dth.13061
Abstract: Currently seldom cases have been reported that generalized morphea could accompany with organ dysfunction. However, our study reveals not only morphea could complicate with intranet organ involvements but it may also be the early phase… read more here.
Keywords: complicated pulmonary; immunosuppression morphea; early immunosuppression; efficacy early ... See more keywords
Efficacy of early transfusion of convalescent plasma with high‐titer SARS‐CoV‐2 neutralizing antibodies in hospitalized patients with COVID‐19
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DOI: 10.1111/trf.16863
Abstract: Despite most controlled trials have shown no measurable benefit of COVID‐19 convalescent plasma (CCP) in patients with COVID‐19, some studies suggest that early administration of CCP with high‐titer anti‐SARS‐CoV‐2 can be beneficial in selected patients.… read more here.
Keywords: high titer; efficacy early; patients covid; convalescent plasma ... See more keywords