A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens
Sign Up to like & getrecommendations! Published in 2020 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.0c00223
Abstract: Semisynthetic rifamycin derivatives such as rifampicin (Rif) are first line treatments for tuberculosis and other bacterial infections. Historically, synthetic modifications made to the C-3/C-4 region of the rifamycin naphthalene core, like those seen in Rif,… read more here.
Keywords: semisynthetic kanglemycin; efficacy high; shows vivo; kanglemycin shows ... See more keywords
Bactericidal Efficacy of High Irradiance Ultraviolet A Photoactivation of Riboflavin Versus Standard Corneal Cross-Linking Protocol In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Cornea"
DOI: 10.1097/ico.0000000000003031
Abstract: Purpose: The purpose of this study was to compare the efficacy of high ultraviolet A (UVA) irradiance photoactivation of riboflavin (vitamin B2) versus the standard corneal cross-linking protocol on bacterial viability. Methods: Methicillin-sensitive Staphylococcus aureus… read more here.
Keywords: efficacy high; corneal cross; irradiance; photoactivation riboflavin ... See more keywords
The safety and early efficacy of high-dose ipilimumab (IPI) and the combination nivolumab plus ipilimumab (NIVO + IPI) in patients (pts) with uveal melanoma (UM).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.9554
Abstract: 9554Background: UM metastases occur in 50% of cases and high-risk pts are identified by a gene expression profile. High-dose IPI is approved for adjuvant (adj) treatment (tx) of cutaneous melanoma ... read more here.
Keywords: melanoma; early efficacy; ipi; high dose ... See more keywords