Defensive efficacy interim design: Dynamic benefit/risk ratio view using probability of success
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DOI: 10.1080/10543406.2016.1198370
Abstract: ABSTRACT Traditional efficacy interim design is based on alpha spending which does not have intuitive interpretation and hence is difficult to communicate with non-statistician colleagues. The alpha-spending approach is based on efficacy alone and hence… read more here.
Keywords: interim design; probability success; efficacy interim; efficacy ... See more keywords