Efficacy and mechanism of cGAMP to suppress Alzheimer’s disease by elevating TREM2
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.07.004
Abstract: Innate immune responses are considered to play crucial roles in the progression of Alzheimer's disease (AD). Recently, immunotherapy is emerging as an innovative and highly conceivable strategy for AD treatment. The cGAMP-STING-IRF3 signaling pathway plays… read more here.
Keywords: efficacy mechanism; alzheimer disease; cgamp; mechanism cgamp ... See more keywords
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81343-z
Abstract: New antimalarial therapeutics are needed to ensure that malaria cases continue to be driven down, as both emerging parasite resistance to frontline chemotherapies and mosquito resistance to current insecticides threaten control programmes. Plasmodium, the apicomplexan… read more here.
Keywords: efficacy mechanism; mechanism; ddd01034957; resistance ... See more keywords