Efficacy of melatonin in term neonatal models of perinatal hypoxia‐ischaemia
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51559
Abstract: Neonatal encephalopathy (NE) is an important cause of mortality and disability worldwide. Therapeutic hypothermia (HT) is an effective therapy, however not all babies benefit. Novel agents are urgently needed to improve outcomes. Melatonin in preclinical… read more here.
Keywords: efficacy melatonin; term neonatal; neonatal models; melatonin term ... See more keywords
Efficacy of melatonin in the treatment of patients with COVID‐19: A systematic review and meta‐analysis of randomized controlled trials
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DOI: 10.1002/jmv.27595
Abstract: This study investigated the effect of melatonin on clinical outcomes in patients with coronavirus disease 2019 (COVID‐19). We searched PubMed, the Web of Science, the Cochrane Library, Ovid MEDLINE, and Clinicaltrials.gov for randomized controlled trials… read more here.
Keywords: efficacy melatonin; randomized controlled; controlled trials; treatment ... See more keywords
Screening the Efficacy of Melatonin on Neurodegeneration Mediated by Endoplasmic Reticulum Stress, Inflammation, and Oxidative Damage
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-022-03814-x
Abstract: Neurodegeneration may be defined as a clinical condition wherein neurons gradually lose their structural integrity, viability, and functional abilities and the damage inflicted upon the neurons is often irreversible. The various mechanisms that have been… read more here.
Keywords: damage; efficacy melatonin; neurodegeneration; oxidative damage ... See more keywords
The efficacy of melatonin and melatonin agonists in insomnia - An umbrella review.
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DOI: 10.1016/j.jpsychires.2019.10.022
Abstract: We conducted an umbrella review to summarize all available systematic reviews and meta-analyses investigating the efficacy of melatonin and melatonin agonists in primary and comorbid insomnia disorders. Two independent reviewers conducted a search of Pubmed,… read more here.
Keywords: umbrella review; efficacy melatonin; melatonin agonists; melatonin ... See more keywords
What do we really know about the safety and efficacy of melatonin for sleep disorders?
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DOI: 10.1080/03007995.2021.2000714
Abstract: Melatonin is a hormonal product of the pineal gland, a fact that is often forgotten. Instead it is promoted as a dietary supplement that will overcome insomnia, as an antioxidant and as a prescription only… read more here.
Keywords: melatonin sleep; drug; efficacy melatonin; sleep disorders ... See more keywords
Application and Efficacy of Melatonin Elastic Liposomes in Photoaging Mice
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DOI: 10.1155/2022/7135125
Abstract: Transdermal drug delivery system is a preferable choice to overcome the low bioavailability of oral medication. Elastic liposomes have shown great effectiveness for percutaneous transport of melatonin (MLT). In this study, the elastic liposomes loaded… read more here.
Keywords: elastic liposomes; application efficacy; efficacy melatonin; melatonin elastic ... See more keywords