Articles with "efficacy piperazine" as a keyword



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Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

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Published in 2018 at "PLoS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0006183

Abstract: Cryptosporidiosis causes life-threatening diarrhea in infants, but the best available treatment is only modestly efficacious. Rodents infected with relevant Cryptosporidium species do not develop diarrhea, which complicates drug development. Cryptosporidium parvum infection of dairy calves,… read more here.

Keywords: clinical microbiologic; drug; piperazine based; efficacy piperazine ... See more keywords