Efficacy of remdesivir in a rhesus macaque model of MERS-CoV infection
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DOI: 10.1038/s41684-020-0537-x
Abstract: Remdesivir (GS-5734), a drug developed by Gilead Sciences, is currently under trial for the treatment of COVID-19, the disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Remdesivir, a nucleotide analogue that blocks viral… read more here.
Keywords: rhesus; efficacy remdesivir; disease; efficacy ... See more keywords
Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola
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DOI: 10.1128/aac.01117-21
Abstract: Remdesivir is a nucleoside monophosphoramidate prodrug that has been FDA approved for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of remdesivir for COVID-19 remains contentious, as several trials have not found statistically significant differences… read more here.
Keywords: efficacy remdesivir; remdesivir covid; remdesivir; clinical efficacy ... See more keywords