Inhibition of KU70 and KU80 by CRISPR interference, not NgAgo interference, increases the efficiency of homologous recombination in pig fetal fibroblasts
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DOI: 10.1016/s2095-3119(18)62150-1
Abstract: Abstract Non-homologous end-joining (NHEJ) is a predominant pathway for the repair of DNA double-strand breaks (DSB). It inhibits the efficiency of homologous recombination (HR) by competing for DSB targets. To improve the efficiency of HR,… read more here.
Keywords: efficiency homologous; ku70 ku80; homologous recombination; interference ... See more keywords