The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors
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DOI: 10.18632/oncotarget.25158
Abstract: Y-box-binding protein 1 (YB-1) is a multifunctional cellular factor overexpressed in tumors resistant to chemotherapy. An intrinsically disordered structure together with a high positive charge peculiar to YB-1 allows this protein to function in almost… read more here.
Keywords: protein; efficiency parp1; parp1 inhibitors; parp1 ... See more keywords