Electrochemical Direct Thiolation of Lactams with Mercaptans: An Efficient Access to N-Acylsulfenamides
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202100924
Abstract: A variety of N‐acylsulfenamides are produced by the electrochemically enabled cross‐coupling of readily available feedstocks under standard conditions. This protocol is practical and has wide substrate scope with good reaction efficiency (38 examples, up to… read more here.
Keywords: thiolation lactams; lactams mercaptans; mercaptans efficient; electrochemical direct ... See more keywords
Efficient Access to 3D Mesoscopic Prisms in Polymeric Soft Materials.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202100064
Abstract: The preparation of 3D functional isolated mesoscopic assemblies remains a challenge in the self-assembly of polymers. Here, well-defined 3D hexagonal and hexagram prisms with uniform dimensions are acquired by the crystallization of the inclusion complex… read more here.
Keywords: soft materials; efficient access; access mesoscopic; mesoscopic prisms ... See more keywords
Facile and efficient access to Androsten-17-(1',3',4')-pyrazoles and Androst-17β-(1',3',4')-pyrazoles via Vilsmeier reagents, and their antiproliferative activity evaluation in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.02.033
Abstract: In this work, twenty-seven novel steroidal pyrazole derivatives were designed and effectively synthesized with two different commercially available staring material, Isopregnanolone 1 and 5,16-Pregnadienolone 7, via the key intermediates, 17β-(4'-formyl)pyrazolylandrost-3β-yl formate and 17-(4'-formyl)pyrazolylandrost- 5,16-dienes-3β-yl formate,… read more here.
Keywords: cell lines; facile efficient; efficient access; vilsmeier ... See more keywords
An Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b08794
Abstract: Azobenzenes are versatile photoswitches that have found widespread use in a variety of fields, ranging from photo-pharmacology to the material sciences. In addition to regular azobenzenes the cyclic diazocines have recently emerged. Although diazocines have… read more here.
Keywords: access cyclic; approach enables; efficient access; enables efficient ... See more keywords
Efficient access to bisphenol A metabolites: Synthesis of monocatechol, mono-o-quinone, dicatechol, and di-o-quinone of bisphenol A
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2017.1390586
Abstract: ABSTRACT 2-Iodoxybenzoic acid (IBX) oxidation of bisphenol A (BPA) is described. The selective production of either the mono-o-quinone or the di-o-quinone can be controlled by IBX stoichiometry. Isolated yields of quinone were greater than 80%.… read more here.
Keywords: bisphenol; quinone; mono quinone; efficient access ... See more keywords
Efficient access to domain-integrated estradiol-flavone hybrids via the corresponding chalcones and their in vitro anticancer potential
Sign Up to like & getrecommendations! Published in 2022 at "Steroids"
DOI: 10.2139/ssrn.4120924
Abstract: Structural modification of the phenolic A-ring of estrogens at C-2 and/or C-3 significantly reduces or eliminates the hormonal effects of the compounds, thus the incorporation of other pharmacophores into these positions can provide biologically active… read more here.
Keywords: estradiol flavone; flavone hybrids; access domain; efficient access ... See more keywords
Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers’ Lactamization
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16030413
Abstract: The concept of privileged structure has been used as a fruitful approach for the discovery of novel biologically active molecules. A privileged structure is defined as a semi-rigid scaffold able to display substituents in multiple… read more here.
Keywords: bio inspired; tricyclic spirolactams; novel; efficient access ... See more keywords