Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox
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DOI: 10.1002/cctc.201701379
Abstract: Chiral secondary and tertiary amines are ubiquitous in pharmaceutical, fine, and specialty chemicals, but their synthesis typically suffers from significant sustainability and selectivity challenges. Biocatalytic alternatives, such as enzyme‐catalyzed reductive amination, offer several advantages over… read more here.
Keywords: aminations extending; imine reductase; biocatalytic reductive; efficient biocatalytic ... See more keywords
The first efficient biocatalytic route for the synthesis of Kojic acid derivatives in aqueous media
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DOI: 10.1016/j.catcom.2021.106289
Abstract: Abstract The first efficient biocatalytic route for the synthesis of kojic acid derivatives was developed in presence of an enzyme. In this process, benzaldehydes, malononitrile and kojic acid were used as starting materials while lipase… read more here.
Keywords: acid derivatives; efficient biocatalytic; first efficient; kojic acid ... See more keywords
Highly efficient biocatalytic cascade for the diversity-oriented synthesis of complex blood group Sdaantigens
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DOI: 10.1039/d0gc02971h
Abstract: Highly efficient multienzyme cascade synthesis of 15 naturally occurring complex Sdaantigens. read more here.
Keywords: synthesis; efficient biocatalytic; cascade; cascade diversity ... See more keywords
Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations
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DOI: 10.3390/molecules25040934
Abstract: The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in transglycosylation reactions… read more here.
Keywords: thermodynamic calculations; dihalogenated nucleoside; biocatalytic synthesis; efficient biocatalytic ... See more keywords