Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202006892
Abstract: Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by converting intracellular hydrogen peroxide (H2 O2 ) into highly toxic hydroxyl radicals (• OH). To overcome the current limitations of the insufficient… read more here.
Keywords: nanocatalytic theranostics; cancer therapy; cancer; therapy ... See more keywords
Rationally Designed Monodisperse Gd2 O3 /Bi2 S3 Hybrid Nanodots for Efficient Cancer Theranostics.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201802904
Abstract: Multifunctional nanotheranostic agents are of particular importance in the field of precise nanomedicine. However, a critical challenge remains in the rational fabrication of monodisperse multicomponent nanoparticles with enhanced multifunctional characteristics for efficient cancer theranostics. Here,… read more here.
Keywords: gd2; hybrid nanodots; monodisperse gd2; efficient cancer ... See more keywords
A nano-cocktail of an NIR-II emissive fluorophore and organoplatinum(ii) metallacycle for efficient cancer imaging and therapy† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02466b
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc02466b
Abstract: A novel NIR-II theranostic nanoprobe, PSY (∼110 nm), was concisely developed, which demonstrated excellent photostability, high tumor uptake, superior S/N ratios and more efficient cancer treatment with minimal side effects than cisplatin. read more here.
Keywords: emissive fluorophore; cocktail nir; nano cocktail; nir emissive ... See more keywords
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.ade0059
Abstract: CRISPR-Cas9 has been used successfully to introduce indels in somatic cells of rodents; however, precise editing of single nucleotides has been hampered by limitations of flexibility and efficiency. Here, we report technological modifications to the… read more here.
Keywords: crispr cas9; efficient cancer; modeling crispr; cancer modeling ... See more keywords