Optimized base editors enable efficient editing in cells, organoids and mice
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DOI: 10.1038/nbt.4194
Abstract: CRISPR base editing enables the creation of targeted single-base conversions without generating double-stranded breaks. However, the efficiency of current base editors is very low in many cell types. We reengineered the sequences of BE3, BE4Gam,… read more here.
Keywords: enable efficient; editors enable; base editors; base ... See more keywords