Manganes-Porphyrin as Efficient Enantioselective Catalyst for Aerobic Epoxidation of Olefins
Sign Up to like & getrecommendations! Published in 2018 at "Catalysis Letters"
DOI: 10.1007/s10562-018-2447-8
Abstract: A chiral manganese porphyrin, [Mn(TCPP-Ind)Cl], was synthesized using cis-1-amino-2-indanol substituent. It showed remarkable catalytic activity and enantioselectivity in the epoxidation of olefins with O2/RCHO. Terminal olefins and styrene derivatives were successfully oxidized (> 99% ee). TON… read more here.
Keywords: manganes porphyrin; efficient enantioselective; epoxidation; enantioselective catalyst ... See more keywords
Efficient Enantioselective Syntheses of (+)-Dalesconol A and B.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b00783
Abstract: We herein report the first enantioselective syntheses of immunosuppressants (+)-dalesconol A and B in a highly efficient and concise manner, which features an efficient palladium-catalyzed enantioselective dearomative cyclization-kinetic resolution cascade to install the chiral all-carbon… read more here.
Keywords: syntheses dalesconol; enantioselective syntheses; efficient enantioselective;
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemistry"
DOI: 10.1038/s41557-021-00833-9
Abstract: The combination of computational design and directed evolution could offer a general strategy to create enzymes with new functions. So far, this approach has delivered enzymes for a handful of model reactions. Here we show… read more here.
Keywords: efficient enantioselective; enzyme; morita baylis; baylis hillman ... See more keywords
A new and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil
Sign Up to like & getrecommendations! Published in 2017 at "New Journal of Chemistry"
DOI: 10.1039/c6nj02928k
Abstract: A concise and efficient enantioselective synthesis of both enantiomers of bepridil, a calcium channel blocker, is reported. Jacobsen's hydrolytic kinetic resolution method was utilized to resolve racemic 2-(isobutoxymethyl)oxirane. The incorporation of the succinimide moiety by… read more here.
Keywords: efficient enantioselective; calcium channel; channel blocker; synthesis enantiomers ... See more keywords
Highly efficient enantioselective synthesis of bispiro[benzofuran-oxindole-pyrrolidine]s through organocatalytic cycloaddition
Sign Up to like & getrecommendations! Published in 2019 at "Organic Chemistry Frontiers"
DOI: 10.1039/c9qo00241c
Abstract: The first organocatalyzed [3 + 2] cyclisation of N-2,2,2-trifluoroethylisatin ketimines with aurones has been developed. read more here.
Keywords: synthesis bispiro; efficient enantioselective; enantioselective synthesis; bispiro benzofuran ... See more keywords
Highly efficient and enantioselective synthesis of chiral lactones via Ir-catalysed asymmetric hydrogenation of ketoesters.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02069f
Abstract: Owing to the biological significance and great synthetic value of chiral lactones and their derivatives, increasing attention has been paid to developing effective synthetic methods for chiral lactones. We herein report an efficient asymmetric hydrogenation… read more here.
Keywords: enantioselective synthesis; highly efficient; asymmetric hydrogenation; efficient enantioselective ... See more keywords