An Efficient and Facile Synthesis of Functionalized Indole-3-yl Pyrazole Derivatives Starting from 3-Cyanoacetylindole
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.2654
Abstract: The versatile hitherto reported 3-(1H-indol-3-yl)-1H-pyrazol-5-amine () was synthesized by the reaction of 3-cyanoacetylindole () with hydrazine hydrate in refluxing ethanol and used as a key intermediate for the synthesis of novel pyrazolo[1,5-a]pyrimidines via its reactions… read more here.
Keywords: pyrazole; synthesis functionalized; facile synthesis; functionalized indole ... See more keywords
Efficient and facile ‘on-solvent’ multicomponent synthesis of medicinally privileged pyrano[3,2-c]pyridine scaffold
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DOI: 10.1007/s11164-018-3301-8
Abstract: The new type of ‘on-solvent’ multicomponent reaction was found: transformation of benzaldehydes, malononitrile and 4–hydroxy-6-methylpyridin-2(1H)-one in the presence of sodium acetate as catalyst in a small amount of ethanol results in formation of substituted 2-amino-7-methyl-5-oxo-4-phenyl-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles… read more here.
Keywords: pyrano pyridine; pyridine; solvent multicomponent; efficient facile ... See more keywords
Efficient and Facile End Group Control of Living Ring-Opening Metathesis Polymers via Single Addition of Functional Cyclopropenes
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DOI: 10.1021/acsmacrolett.8b00347
Abstract: Living ROMP has become an important technique for preparing well-controlled, highly functional polymers; however, installing functional groups at the end of living ROMP polymers is not as straightforward as ROMP itself. We report a simple,… read more here.
Keywords: chain end; addition; end; single addition ... See more keywords