Genomics‐Guided Efficient Identification of 2,5‐Diketopiperazine Derivatives from Actinobacteria
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200502
Abstract: Secondary metabolites derived from microorganism constitute an important part of natural products. Mining of the microbial genomes revealed a large number of uncharacterized biosynthetic gene clusters, indicating their greater potential to synthetize specialized or secondary… read more here.
Keywords: identification diketopiperazine; efficient identification; identification; diketopiperazine derivatives ... See more keywords
The Use of ATR-FTIR in Conjunction with Thermal Analysis Methods for Efficient Identification of Polymer Samples: A Qualitative Multi-instrument Instrumental Analysis Laboratory Experiment
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemical Education"
DOI: 10.1021/acs.jchemed.6b00438
Abstract: A multi-instrument approach has been applied to the efficient identification of polymers in an upper-division undergraduate instrumental analysis laboratory course. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) is used in conjunction with differential scanning… read more here.
Keywords: multi instrument; analysis laboratory; analysis; instrumental analysis ... See more keywords
Simulations and active learning enable efficient identification of an experimentally-validated broad coronavirus inhibitor
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62139-5
Abstract: Drug screening resembles finding a needle in a haystack: identifying a few effective inhibitors from a large pool of potential drugs. Large experimental screens are expensive and time-consuming, while virtual screening trades off computational efficiency… read more here.
Keywords: simulations active; active learning; efficient identification; inhibitor ... See more keywords
Efficient identification of geometric inverse sources of parabolic problems by model order reduction
Sign Up to like & getrecommendations! Published in 2025 at "Inverse Problems"
DOI: 10.1088/1361-6420/add17d
Abstract: This article investigates reduced-order models for efficiently solving geometric inverse source problems in parabolic equations. To reconstruct source supports in diffusion processes, a reduced-order approach combining proper orthogonal decomposition and incremental singular value decomposition is… read more here.
Keywords: inverse; identification geometric; inverse sources; efficient identification ... See more keywords
Efficient Identification of Critical Faults in Memristor-Based Inferencing Accelerators
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems"
DOI: 10.1109/tcad.2021.3102894
Abstract: Deep neural networks (DNNs) are becoming ubiquitous, but hardware-level reliability is a concern when DNN models are mapped to emerging neuromorphic technologies such as memristor-based crossbars. As DNN architectures are inherently fault tolerant and many… read more here.
Keywords: critical faults; efficient identification; accuracy; identification critical ... See more keywords
Sample-efficient identification of high-dimensional antibiotic synergy with a normalized diagonal sampling design
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010311
Abstract: Antibiotic resistance is an important public health problem. One potential solution is the development of synergistic antibiotic combinations, in which the combination is more effective than the component drugs. However, experimental progress in this direction… read more here.
Keywords: efficient identification; sample efficient; identification high; design ... See more keywords
Efficient Identification of the MYC Regulator with the Use of the CRISPR Library and Context-Matched Database Screenings
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147723
Abstract: MYC is a major oncogene that plays an important role in cell proliferation in human cancers. Therefore, the mechanism behind MYC regulation is a viable therapeutic target for the treatment of cancer. Comprehensive and efficient… read more here.
Keywords: efficient identification; matched database; myc; crispr library ... See more keywords