4‐Fluorobenzylpiperazine‐Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase
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DOI: 10.1002/cmdc.202000125
Abstract: Tyrosinase is a type‐3 copper protein involved in the biosynthesis of melanin pigments; therefore, the inhibition of its enzymatic activity represents a promising strategy for the treatment of hyperpigmentation‐related disorders. To address this point, we… read more here.
Keywords: derivatives efficient; containing derivatives; fluorobenzylpiperazine containing; tyrosinase ... See more keywords
Inorganic Nanomaterials as Highly Efficient Inhibitors of Cellular Hepatic Fibrosis.
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DOI: 10.1021/acsami.8b10527
Abstract: Chronic liver dysfunction usually begins with hepatic fibrosis. To date, no effective anti-fibrotic drugs have been approved for clinical use in humans. In the current work, titanium dioxide (TiO2) nanoparticles (NPs) and silicon dioxide (SiO2)… read more here.
Keywords: inorganic nanomaterials; fibrosis; nanomaterials highly; hepatic fibrosis ... See more keywords
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12020099
Abstract: Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and preliminary… read more here.
Keywords: natural chalcones; analogues natural; chalcones efficient; inhibitors akr1c3 ... See more keywords