An efficient, scalable approach to hydrolyze flavonoid glucuronides via activation of glycoside bond
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.02.039
Abstract: Abstract Hydrolyzing flavonoid glucuronides into corresponding aglycones posed some significant challenges. To improve acid-catalyzed hydrolysis process of flavonoid glucuronide, structures of glucuronide, hydrolysis parameters and post-processing were optimized. The optimized condition was performed by hydrolysis… read more here.
Keywords: flavonoid glucuronides; scalable approach; glycoside; efficient scalable ... See more keywords
An efficient and scalable synthesis of potent TLR2 agonistic PAM2CSK4
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra01387j
Abstract: Diacylated PAM2CSK4, a highly expensive lipopeptide with desirable aqueous solubility and a broad spectrum of cytokine/chemokine induction is a most potent dual (human and murine) Toll-Like Receptor-2 (TLR2) agonist. Besides such thrilling characteristics, its synthetic… read more here.
Keywords: synthesis potent; efficient scalable; scalable synthesis; synthesis ... See more keywords
An efficient and scalable process to produce morpholine-d8
Sign Up to like & getrecommendations! Published in 2017 at "Synthetic Communications"
DOI: 10.1080/00397911.2016.1266502
Abstract: ABSTRACT Incorporation of isotopes has long been used as a research tool to label carbons and elucidate biochemical pathways. More recently, H→D exchange has led to analogs of therapeutic agents with improved metabolic stability and… read more here.
Keywords: produce morpholine; scalable process; efficient scalable; process ... See more keywords
EESRA: Energy Efficient Scalable Routing Algorithm for Wireless Sensor Networks
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Access"
DOI: 10.1109/access.2019.2929578
Abstract: Many recent wireless sensor network (WSN) routing protocols are enhancements to address specific issues with the “low-energy adaptive clustering hierarchy” (LEACH) protocol. Since the performance of LEACH deteriorates sharply with increasing network size, the challenge… read more here.
Keywords: wireless sensor; efficient scalable; routing algorithm; energy efficient ... See more keywords
SMURF: Efficient and Scalable Metadata Access for Distributed Applications
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Parallel and Distributed Systems"
DOI: 10.1109/tpds.2022.3175596
Abstract: In parallel with big data processing and analysis dominating the usage of distributed and Cloud infrastructures, the demand for distributed metadata access and transfer has increased. The volume of data generated by many application domains… read more here.
Keywords: access distributed; scalable metadata; metadata access; efficient scalable ... See more keywords
Simplitigs as an efficient and scalable representation of de Bruijn graphs
Sign Up to like & getrecommendations! Published in 2021 at "Genome Biology"
DOI: 10.1186/s13059-021-02297-z
Abstract: de Bruijn graphs play an essential role in bioinformatics, yet they lack a universal scalable representation. Here, we introduce simplitigs as a compact, efficient, and scalable representation, and ProphAsm, a fast algorithm for their computation.… read more here.
Keywords: scalable representation; bruijn graphs; efficient scalable; representation ... See more keywords