Efficient Screening of Target‐Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200163
Abstract: Ligand‐based 19F NMR screening is a highly effective and well‐established hit‐finding approach. The high sensitivity to protein binding makes it particularly suitable for fragment screening. Different criteria can be considered for generating fluorinated fragment libraries.… read more here.
Keywords: 19f nmr; chemical shifts; nmr chemical; predicted 19f ... See more keywords
Establishment and evaluation of a method for efficient screening of Clostridium butyricum
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DOI: 10.1007/s12223-020-00803-7
Abstract: At present, the traditional methods for the screening of Clostridium butyricum are not sufficiently selective and efficient. Therefore, it is necessary to establish a targeted and efficient screening method for the detection of C. butyricum.… read more here.
Keywords: clostridium butyricum; butyricum; efficient screening; screening clostridium ... See more keywords
Microfluidic triple-gradient generator for efficient screening of chemical space.
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DOI: 10.1016/j.talanta.2019.06.018
Abstract: Generation of a combinatorial gradient for multiple chemicals is essential for studies of biochemical stimuli, chemoattraction, protein crystallization and others. While currently available platforms require complex design/settings to obtain a double-gradient chemical matrix, we herein… read more here.
Keywords: screening chemical; space; efficient screening; triple gradient ... See more keywords
A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2
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DOI: 10.3389/fimmu.2021.653189
Abstract: After the pandemic of COVID-19, neutralizing antibodies (NAbs) against SARS-CoV-2 have been developed for the prophylactic and therapeutic purposes. However, few methodologies are described in detail on how to rapidly and efficiently generate effective NAbs… read more here.
Keywords: rapid efficient; efficient screening; system neutralizing; neutralizing antibodies ... See more keywords