Computationally efficient whole-genome regression for quantitative and binary traits.
Sign Up to like & getrecommendations! Published in 2021 at "Nature genetics"
DOI: 10.1038/s41588-021-00870-7
Abstract: Genome-wide association analysis of cohorts with thousands of phenotypes is computationally expensive, particularly when accounting for sample relatedness or population structure. Here we present a novel machine-learning method called REGENIE for fitting a whole-genome regression… read more here.
Keywords: whole genome; regression; efficient whole; computationally efficient ... See more keywords
Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology for Biofuels"
DOI: 10.1186/s13068-017-0796-y
Abstract: BackgroundCost-efficient saccharification is one of the main bottlenecks for industrial lignocellulose conversion. Clostridium thermocellum naturally degrades lignocellulose efficiently using the cellulosome, a multiprotein supermolecular complex, and thus can be potentially used as a low-cost catalyst… read more here.
Keywords: whole cell; efficient whole; thermocellum; saccharification ... See more keywords