Structural mass spectrometry approaches to understand multidrug efflux systems
Sign Up to like & getrecommendations! Published in 2022 at "Essays in Biochemistry"
DOI: 10.1042/ebc20220190
Abstract: Abstract Multidrug efflux pumps are ubiquitous across both eukaryotes and prokaryotes, and have major implications in antimicrobial and multidrug resistance. They reside within cellular membranes and have proven difficult to study owing to their hydrophobic… read more here.
Keywords: mass spectrometry; structural mass; efflux; efflux systems ... See more keywords
Iron homeostasis in Bacillus subtilis relies on three differentially expressed efflux systems
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DOI: 10.1099/mic.0.001289
Abstract: In Bacillus subtilis, iron homeostasis is maintained by the ferric uptake regulator (Fur) and manganese homeostasis relies on the manganese transport regulator (MntR). Both Fur and MntR function as bi-functional metalloregulators that repress import and… read more here.
Keywords: bacillus subtilis; iron; iron homeostasis; efflux systems ... See more keywords
Vibrio cholerae OmpR Represses the ToxR Regulon in Response to Membrane Intercalating Agents That Are Prevalent in the Human Gastrointestinal Tract
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DOI: 10.1128/iai.00912-19
Abstract: Multidrug efflux systems belonging to the resistance-nodulation-division (RND) superfamily are ubiquitous in Gram-negative bacteria. RND efflux systems are often associated with multiple antimicrobial resistance and also contribute to the expression of diverse bacterial phenotypes including… read more here.
Keywords: efflux systems; rnd efflux; virulence; vibrio cholerae ... See more keywords
Vibrio cholerae RND efflux systems: mediators of stress responses, colonization and pathogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1203487
Abstract: Resistance Nodulation Division (RND) efflux systems are ubiquitous transporters in gram-negative bacteria that provide protection against antimicrobial agents and thereby enhance survival in virtually all environments these prokaryotes inhabit. Vibrio cholerae is a dual lifestyle… read more here.
Keywords: vibrio cholerae; rnd efflux; efflux systems; colonization ... See more keywords