Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition.
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DOI: 10.1016/j.bbrc.2018.07.035
Abstract: Genetic amplification, overexpression, and increased signaling from the epidermal growth factor receptor (EGFR) are often found in oral squamous cell carcinoma (OSCC) and thus EGFR is frequently targeted molecularly by the therapeutic antibody cetuximab. We… read more here.
Keywords: egf driven; egfr; oral squamous; oscc cells ... See more keywords