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Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk.

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Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.10.025

Abstract: Lithium chloride (LiCl) is an important mood-stabilizing therapeutic agent for bipolar disorders, which has also been shown to inhibit cancer cell metastasis. Investigations of LiCl-induced signaling have focused mainly on extracellular signal regulated kinase 1/2… read more here.

Keywords: treatment; erk; lithium chloride; osteosarcoma cells ... See more keywords