Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno‐associated virus delivery in adult rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24183
Abstract: Recombinant adeno‐associated viral (AAV)‐mediated therapeutic gene transfer to dorsal root ganglia (DRG) is an effective and safe tool for treating chronic pain. However, AAV with various constitutively active promoters leads to transgene expression predominantly to… read more here.
Keywords: cmv; expression; promoter; transduction ... See more keywords
N'-(3-Aminopropyl)-N-(3'-(carbamoyl cholesteryl) propyl)-glycine amide liposomes for delivery of pTRAIL-EGFP.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of liposome research"
DOI: 10.1080/08982104.2023.2193638
Abstract: In this study, N'-(3-aminopropyl)-N-(3'-(carbamoyl cholesteryl) propyl)-glycine amide (A) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE, D) (AD) liposomes were synthesised at molar ratios of 50:25 (AD5025), 50:50 (AD5050) and 50:75 (AD5075) and complexed with plasmid, pTRAIL-EGFP. AD liposome/pTRAIL-EGFP were… read more here.
Keywords: egfp; aminopropyl carbamoyl; carbamoyl cholesteryl; liposome ptrail ... See more keywords
Recombinant Adeno-Associated Virus Vector Mediated Gene Editing in Proliferating and Polarized Cultures of Human Airway Epithelial Cells
Sign Up to like & getrecommendations! Published in 2025 at "Human Gene Therapy"
DOI: 10.1089/hum.2024.260
Abstract: Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. While CRISPR-based CFTR editing approaches have shown proof-of-concept for functional rescue in primary airway basal cells, induced pluripotent stem… read more here.
Keywords: gene editing; egfp; human airway; cftr ... See more keywords
Attenuation of Simian Varicella Virus Infection by Enhanced Green Fluorescent Protein in Rhesus Macaques
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.02253-17
Abstract: ABSTRACT Simian varicella virus (SVV), the primate counterpart of varicella-zoster virus, causes varicella (chickenpox), establishes latency in ganglia, and reactivates to produce zoster. We previously demonstrated that a recombinant SVV expressing enhanced green fluorescent protein… read more here.
Keywords: rhesus macaques; varicella; svv; virus ... See more keywords
Corneal Reconstruction with EGFP-Labelled Limbal Mesenchymal Stem Cells in a Rabbit Model of Limbal Stem Cell Deficiency
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065431
Abstract: Ocular surface reconstruction is essential for treating corneal epithelial defects and vision recovery. Stem cell-based therapy demonstrates promising results but requires further research to elucidate stem cell survival, growth, and differentiation after transplantation in vivo.… read more here.
Keywords: egfp; stem cell; transplantation; reconstruction ... See more keywords
Transfer of cardiomyocyte-derived extracellular vesicles to neighboring cardiac cells requires tunneling nanotubes during heart development
Sign Up to like & getrecommendations! Published in 2024 at "Theranostics"
DOI: 10.7150/thno.91604
Abstract: Rationale: Extracellular vesicles (EVs) are thought to mediate intercellular communication during development and disease. Yet, biological insight to intercellular EV transfer remains elusive, also in the heart, and is technically challenging to demonstrate. Here, we… read more here.
Keywords: extracellular vesicles; egfp; heart; transfer ... See more keywords