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   Articles with "egfr akt" as a keyword



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Dihydromyricetin suppresses tumor growth via downregulation of the EGFR/Akt/survivin signaling pathway.

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recommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23328

Abstract: Deregulation of epidermal growth factor receptor (EGFR) signaling is frequently observed in non‐small cell lung cancer (NSCLC). The present study aimed to determine the impact of dihydromyricetin (DHM) on NSCLC, a natural compound extracted from… read more here.

Keywords: egfr akt; growth; dhm; present study ... See more keywords
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miR-4461 inhibits the progression of Gallbladder carcinoma via regulating EGFR/AKT signaling

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2042775

Abstract: ABSTRACT Increasing evidence has demonstrated that microRNAs (miRNAs) participated in the tumorigenesis, progression and recurrence of various malignancies including Gallbladder carcinoma (GBC). miR-4461 was reported to work as a tumor suppressor gene in renal cell… read more here.

Keywords: egfr akt; progression; gbc; gallbladder ... See more keywords
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Oxidative stress affects retinal pigment epithelial cell survival through epidermal growth factor receptor/AKT signaling pathway.

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recommendations! Published in 2017 at "International journal of ophthalmology"

DOI: 10.18240/ijo.2017.04.02

Abstract: AIM To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS Human RPE cell lines (ARPE-19 cell) were treated with different doses… read more here.

Keywords: akt signaling; egfr akt; signaling pathway; cell ... See more keywords
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PLIN2 confers gefitinib resistance by inhibiting cell apoptosis via activation of EGFR/AKT/survivin in PC9R cells

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recommendations! Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.24153

Abstract: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the first-line drugs for advanced non-small cell lung cancer (NSCLC) patients with activating EGFR mutations. However, the development of TKI resistance is a major clinical… read more here.

Keywords: akt survivin; gefitinib resistance; pc9r cells; egfr akt ... See more keywords
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Chlorogenic Acid Inhibition of Esophageal Squamous Cell Carcinoma Metastasis via EGFR/p-Akt/Snail Signaling Pathways

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recommendations! Published in 2022 at "AntiCancer Research"

DOI: 10.21873/anticanres.15826

Abstract: Background/Aim: Chlorogenic acid (CGA) is a polyphenol compound found in a variety of foods, including coffee, tea, cherries, and apples. It has been found by a number of studies to affect the viability of human… read more here.

Keywords: chlorogenic acid; cell; egfr akt; akt snail ... See more keywords

ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway

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recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.618987

Abstract: Background Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant cancers in East Asia, with high incidence and mortality. Accumulating evidence has shown that ATF3 is associated with tumor progression. Methods… read more here.

Keywords: catenin; egfr akt; atf3; cell ... See more keywords
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Scaphium affine Ethanol Extract Induces Anoikis by Regulating the EGFR/Akt Pathway in HCT116 Colorectal Cancer Cells

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recommendations! Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.621346

Abstract: Scaphium affine ethanol extracts (SAE) is a species that has been shown to contain various physiological effects; however, its anticancer effects have yet to be revealed. We qualitatively evaluated β-sitosterol in SAE through high-performance liquid… read more here.

Keywords: colorectal cancer; egfr akt; cancer cells; hct116 colorectal ... See more keywords
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C1orf74 positively regulates the EGFR/AKT/mTORC1 signaling in lung adenocarcinoma cells

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recommendations! Published in 2022 at "PeerJ"

DOI: 10.7717/peerj.13908

Abstract: Background Lung adenocarcinoma (LUAD) is a major type of lung cancer with poor prognosis and low 5-year survival rate, which urgently needs further investigation in order to elucidate its mechanisms completely and discover novel therapeutic… read more here.

Keywords: egfr akt; mtorc1 signaling; luad; akt mtorc1 ... See more keywords