Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.4021
Abstract: Importance The debate about the role of the Food and Drug Administration (FDA) in the regulation of laboratory-developed tests (LDTs) has focused attention on the analytical performance of all clinical laboratory testing. This study provides… read more here.
Keywords: ldts fda; egfr kras; fda cds; braf egfr ... See more keywords
Costs of ALK, ROS1, EGFR, and KRAS testing in non–small cell lung cancer: About different strategies in France
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Cytopathology"
DOI: 10.1002/cncy.21919
Abstract: We read with interest the review by Pisapia et al about perspectives on ALK and ROS1 testing for cytologic lung cancer samples. In addition to fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC), we agree… read more here.
Keywords: cancer; egfr kras; alk ros1; pathology ... See more keywords
Comparison of CT radiogenomic and clinical characteristics between EGFR and KRAS mutations in lung adenocarcinomas.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical radiology"
DOI: 10.1016/j.crad.2018.01.009
Abstract: AIM To compare computed tomography (CT) radiogenomic and clinical characteristics between patients with epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) mutations in lung adenocarcinomas. MATERIALS AND METHODS This study was… read more here.
Keywords: egfr kras; radiogenomic clinical; mutations lung; lung adenocarcinomas ... See more keywords
Predictive radiogenomics modeling of EGFR mutation status in lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41674
Abstract: Molecular analysis of the mutation status for EGFR and KRAS are now routine in the management of non-small cell lung cancer. Radiogenomics, the linking of medical images with the genomic properties of human tumors, provides… read more here.
Keywords: status; egfr mutation; egfr kras; mutation status ... See more keywords
Correlation of EGFR or KRAS mutation status with 18F-FDG uptake on PET-CT scan in lung adenocarcinoma
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DOI: 10.1371/journal.pone.0175622
Abstract: Background 18F-fluoro-2-deoxy-glucose (18F-FDG) positron emission tomography (PET) is a functional imaging modality based on glucose metabolism. The correlation between EGFR or KRAS mutation status and the standardized uptake value (SUV) of 18F-FDG PET scanning has… read more here.
Keywords: kras mutation; egfr kras; lung; mutation status ... See more keywords
Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors.
Sign Up to like & getrecommendations! Published in 2017 at "Acta cirurgica brasileira"
DOI: 10.1590/s0102-865020170030000009
Abstract: Purpose: To evaluate the expression of EGFR, KRAS genes, microRNAs-21 and 203 in colon and rectal cancer samples, correlated with their age at diagnosis, histological subtype, value of pretreatment CEA, TNM staging and clinical outcome.… read more here.
Keywords: egfr kras; rectal cancer; colon rectal; expression ... See more keywords
Detection of EGFR and KRAS gene mutations using suspension liquid-based cytology specimens in metastatic lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22530
Abstract: Background The detection of EGFR and KRAS mutations of metastatic lung adenocarcinoma using liquid-based cytology suspension routine specimens from fine-needle aspiration remains controversial. Results The DNA of all specimens was extracted and real time PCR… read more here.
Keywords: egfr kras; metastatic lung; detection egfr; liquid based ... See more keywords
Imaging of synchronous multiple primary lung adenocarcinoma with concomitant EGFR and KRAS mutations: a case report and review of the literature
Sign Up to like & getrecommendations! Published in 2021 at "Translational cancer research"
DOI: 10.21037/tcr-20-3258
Abstract: With the application of computed tomography (CT) imaging technology, the incidence rate of multiple primary lung cancer has gradually increased. However, the prevalence of concomitant epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral… read more here.
Keywords: primary lung; lung adenocarcinoma; multiple primary; egfr kras ... See more keywords
Simultaneous Identification of EGFR, KRAS, ERBB2, and TP53 Mutations in Patients with Non-Small Cell Lung Cancer by Machine Learning-Derived Three-Dimensional Radiomics
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13081814
Abstract: Simple Summary Multiple genetic mutations are associated with the outcomes of patients with non-small cell lung cancer (NSCLC) after using tyrosine kinase inhibitor, but the cost for detecting multiple genetic mutations is high. Few studies… read more here.
Keywords: machine learning; egfr kras; erbb2 tp53; kras erbb2 ... See more keywords
EGFR, KRAS, and BRAF mutational profiles of female patients with micropapillary predominant invasive lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Turkish journal of medical sciences"
DOI: 10.3906/sag-1612-150
Abstract: Background/aim: This study aimed to analyze EGFR, KRAS, and BRAF mutations in females with micropapillary predominant invasive lung adenocarcinoma and their relationships with immunohistochemical and clinicopathological patterns.Materials and methods: A total of 15 females with… read more here.
Keywords: kras braf; micropapillary predominant; egfr kras; predominant invasive ... See more keywords