Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b00071
Abstract: Large-scale phosphoproteomics with coverage of over 10,000 sites of phosphorylation have now been routinely achieved with advanced mass spectrometry (MS)-based workflows. However, accurate targeted MS-based quantification of phosphorylation dynamics, an important direction for gaining quantitative… read more here.
Keywords: egfr mapk; phosphorylation dynamics; mapk pathway; quantification phosphorylation ... See more keywords
Dihydrochalcone Derivative Induces Breast Cancer Cell Apoptosis via Intrinsic, Extrinsic, and ER Stress Pathways but Abolishes EGFR/MAPK Pathway
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/7298539
Abstract: Dihydrochalcone derivatives are active compounds that have been purified from the Thai medicinal plant Cyathostemma argenteum. The objectives of this study were to investigate the effects of two dihydrochalcone derivatives on human breast cancer MDA-MB-231… read more here.
Keywords: egfr mapk; dihydrochalcone; apoptosis; compound ... See more keywords
Canine oviductal exosomes improve oocyte development via EGFR/MAPK signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction"
DOI: 10.1530/rep-19-0600
Abstract: Oviduct cells produce a favorable environment for the development of gametes by generating multiple growth factors. Particularly, in canine species, immature oocytes undergo serial maturation processes in the oviduct, while the other mammals already possess… read more here.
Keywords: egfr mapk; canine oviductal; oviductal exosomes; via egfr ... See more keywords
Favorable Immune Microenvironment in Patients with EGFR and MAPK Co-Mutations
Sign Up to like & getrecommendations! Published in 2020 at "Lung Cancer: Targets and Therapy"
DOI: 10.2147/lctt.s262822
Abstract: Purpose Although EGFR-mutated patients generally do not benefit from checkpoint inhibitors (ICIs), some patients in the KEYNOTE-001 study consistently benefited from this treatment. This study investigated immune microenvironment characteristics to identify the subgroup of patients… read more here.
Keywords: immune microenvironment; mutated patients; egfr mapk; mapk mutations ... See more keywords
Nucleophosmin promotes lung adenocarcinoma cell proliferation, migration and invasion by activating the EGFR/MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Reports"
DOI: 10.3892/or.2023.8563
Abstract: Lung adenocarcinoma (LUAD) is the main cause of death globally. The present study investigated the prognostic value and functional verification of nucleophosmin (NPM1) in LUAD. LUAD and normal samples from The Cancer Genome Atlas were… read more here.
Keywords: proliferation migration; cell proliferation; luad; migration invasion ... See more keywords