Targeting EGFR‐mediated autophagy as a potential strategy for cancer therapy
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31398
Abstract: Autophagy is a naturally occurring programed cellular catabolic process stimulated by cellular stress for energy homeostasis maintenance and elimination of harmful substances. It mostly works as pro‐survival mechanism but on the other hand deregulation of… read more here.
Keywords: mediated autophagy; signaling pathway; cell death; cancer ... See more keywords
EGFR‐mediated signaling pathway influences the sensitivity of oral squamous cell carcinoma to JQ1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26920
Abstract: Inhibiting BRD4 has emerged as a promising anticancer strategy, and inhibitors such as JQ1 can suppress cell growth in oral squamous cell carcinoma (OSCC). However, the mechanism through which JQ1 exerts its anticancer activity has… read more here.
Keywords: cell; signaling pathway; jq1; mediated signaling ... See more keywords
The Efficient Activity of Glabridin and its Derivatives Against EGFR-mediated Inhibition of Breast Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230303120942
Abstract: BACKGROUND Breast cancer (BC) is one of the most typical causes of cancer death in women worldwide. Activated epidermal growth factor receptor (EGFR) signaling has been increasingly associated with BC development and resistance to cytotoxic… read more here.
Keywords: glabridin derivatives; synthetic drugs; egfr mediated; breast cancer ... See more keywords
Reversing EGFR Mediated Immunoescape by Targeted Monoclonal Antibody Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00332
Abstract: Uncontrolled growth is a signature of carcinogenesis, in part mediated by overexpression or overstimulation of growth factor receptors. The epidermal growth factor receptor (EGFR) mediates activation of multiple oncogenic signaling pathways and escape from recognition… read more here.
Keywords: growth factor; egfr mediated; monoclonal antibody;